A trial of bumetanide (0.25 mg daily) monotherapy was successful in resolution of a patient's symptoms. These results suggest bumetanide could be effective in the treatment of idiopathic intracranial hypertension, perhaps by restoring the balance between cerebrospinal fluid formation and absorption and/or by altering the volume or ionic composition of the brain's extracellular fluid compartment 1).


1)
Kahle KT, Walcott BP, Staley KJ. Resolution of headache and papilledema in idiopathic intracranial hypertension associated with inhibition of Na+-K+-2Cl- cotransport. J Child Neurol. 2011 Feb;26(2):205-8. doi: 10.1177/0883073810391264. PubMed PMID: 21285039.
  • bumetanide.txt
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