Arterial spin labelled imaging for Moyamoya disease
The four-dimensional pseudo-continuous arterial spin labeling (4D-pCASL)-based angiography using CENTRA-keyhole and view sharing (4D-PACK) provided better visualization and higher contrast-to-noise ratio (CNR) in distal cerebral arteries and leptomeningeal anastomosis (LMA) collaterals compared with contrast inherent inflow-enhanced multiphase angiography (CINEMA) 1)
Post-label delay times of ≥4 seconds are needed and may be combined with multidelay strategies for robust ASL assessment of CBF in Moyamoya disease 2).
ASL-PWI may provide a reliable and noninvasive means of predicting angiographic vascularity of meningiomas. It may thus assist in selecting potential candidates for preoperative digital subtraction angiography and embolization in clinical practice. 3).
High-grade pediatric brain tumors display higher CBF than do low-grade tumors, and they may be accurately graded by using these values. CBF is correlated with tumor microvascular density 4).
A study clearly demonstrates that the initial use of ASL and DWI could help to diagnose partial nonconvulsive status epilepticus (NCSE) and also combined use of the MRI and EEG allows documentation of the pathophysiological mechanism in each patient 5).