Anticoagulation Resumption after intracranial hemorrhage
Only randomized controlled trials, either pragmatic or explanatory, can provide more conclusive answers for this important clinical question 1).
In 2018, a systematic review and meta-analysis showed that resuming anticoagulant therapy after interruption for anticoagulation-associated intracranial hemorrhage reduced the risks of thromboembolic events, without significantly increasing the risks of ICH recurrence and long-term mortality 2).
see Anticoagulation Resumption after chronic subdural hematoma.
see Anticoagulation Resumption after intracerebral hemorrhage.
see Anticoagulation Resumption after traumatic brain injury.
1)
Hawkes MA, Rabinstein AA. Anticoagulation for atrial fibrillation after
intracranial hemorrhage: A systematic review. Neurol Clin Pract. 2018
Feb;8(1):48-57. doi: 10.1212/CPJ.0000000000000425. Review. PubMed PMID: 29517050;
PubMed Central PMCID: PMC5839688.
2)
Zhou Z, Yu J, Carcel C, Delcourt C, Shan J, Lindley RI, Neal B, Anderson CS,
Hackett ML. Resuming anticoagulants after anticoagulation-associated intracranial
haemorrhage: systematic review and meta-analysis. BMJ Open. 2018 May
14;8(5):e019672. doi: 10.1136/bmjopen-2017-019672. PubMed PMID: 29764874; PubMed
Central PMCID: PMC5961574.