The Angio-Seal™ Evolution™ is effective at decreasing mean time to hemostasis, like other closing devices. However, it may not be effective at producing early ambulation and discharge, compared to manual compression, because delayed complications may occur significantly after 24 hours 1)


1)
Chung J, Lee DW, Kwon OS, Kim BS, Shin YS. Angio-Seal™ Evolution™ versus Manual Compression for Common Femoral Artery Puncture in Neurovascular Diagnostic Angiography : A Prospective, Non-Randomized Study. J Korean Neurosurg Soc. 2011 Mar;49(3):153-6. doi: 10.3340/jkns.2011.49.3.153. Epub 2011 Mar 31. PubMed PMID: 21556234; PubMed Central PMCID: PMC3085810.
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