Aggressiveness

Spreading rapidly or highly invasive; difficult or impossible to treat successfully.

Aggressiveness has a high prevalence in psychiatric patients and is a major health problem. Two brain areas involved in the neural network of aggressive behavior are the amygdala and the hypothalamus. While pharmacological treatments are effective in most patients, some do not properly respond to conventional therapies and are considered medically refractory.

see Refractory aggressiveness.