A Coruña

• The continued industrial use of ethylene oxide despite health risks: An interventional radiology perspective on a broader medical challenge of balancing sterility, safety, and sustainability
• Global, regional, and national impact of Down syndrome on child and adolescent mortality from 1980 to 2021, with projections to 2050: a cross-sectional study
• Age-related differences in the clinical features and management of pituitary apoplexy: a cohort study
• 30-Day Outcomes of Real-World Elective Carotid Stenosis Treatment Using a Dual-Layer Micromesh Stent (ROADSAVER Study)
• Intercostal serratus plane block versus posterior quadratuus lumbar block in laparoscopic nephrectomy: A randomized, controlled, double-blind study
• The Effect of Rehabilitation Therapy in Children with Intervened Congenital Heart Disease: A Study Protocol of Randomized Controlled Trial Comparing Hospital and Home-Based Rehabilitation
• Sellar and perisellar meningiomas: effects on pituitary function in a Spanish cohort observational study
• Beyond the Operating Room: The Reality of Gender Disparities in Neurosurgical Education Starting in Medical School

Despite the more aggressive behavior of GH&PRL-PitNETs compared to Somatotroph pituitary neuroendocrine tumors, there were no significant differences in the rate of IGF-1 control between the two drugs (pegvisomant and pasireotide) in either patient group. Both drugs were effective in controlling IGF-1 and PRL hypersecretion in the tumors studied. The study found that pegvisomant and pasireotide are both effective treatments for controlling IGF-1 and PRL hypersecretion in patients with GH&PRL-Pit-NETs and GH-Pit-NETs, with no substantial differences in efficacy between the two drugs ¹⁾.

Glucose metabolism improved in patients with acromegaly after surgery and 21% of the diabetic patients experienced diabetes remission; being more frequent in patients of older age, and those who experienced surgical cure and those with preserved anterior pituitary function after surgery ²⁾.

Department of Neurosurgery, Hospital HM Modelo, A Coruña, Spain (Dr Garcia-Fantini)

Synergistic Increase of Serum BDNF in Alzheimer Patients Treated with Cerebrolysin and Donepezil: Association with Cognitive Improvement in ApoE4 Cases

Vivid Mental Imagery of Biomechanically Impossible Movements Elicited by Cortical Electrostimulation of the Central Region in an Awake Patient