1979

1978-1980


Pleomorphic xanthoastrocytoma (PXA) was recognized as a distinct entity in 1979 1)


Pseudoprogression is primarily reported in patients who underwent radiotherapy for high-grade glioma, and was first described by Hoffman et al. in 1979. In a study of 51 patients with high-grade glioma, six patients (12 %) had increased computerized tomography (CT) enhancement following radiation, which later disappeared 2)


On 1 October 1971 the first patient was scanned and the data sent off for analysis. The resulting images were examined by the hospital's neuroradiologists, neurologists and neurosurgeons who immediately appreciated their value. There was international media interest and hundreds of clinicians visited the hospital to see the new scanner. Hounsfield shared the 1979 Nobel Prize in Physiology or Medicine with the physicist Allan M. Cormack “for the development of computer assisted tomography”.


The first edition of the World Health Organization Classification of Tumors of the Central Nervous System was published in 1979 and took almost a decade to complete.

The second edition followed in 1993 and was considered a great step forward as it incorporated the advances in classification resulting from the introduction of immunohistochemistry.


The so-called true posterior communicating artery aneurysm was first described by Yoshida et al. 3) in 1979.


1)
Kepes JJ, Rubinstein LJ, Eng LF (1979) Pleomorphic xanthoastrocytoma: a distinctive meningocerebral glioma of young subjects with relatively favorable prognosis. A study of 12 cases. Cancer 44:1839–1852
2)
Hoffman WF, Levin VA, Wilson CB. Evaluation of malignant glioma patients during the postirradiation period. J Neurosurg. 1979 May;50(5):624-8. doi: 10.3171/jns.1979.50.5.0624. PMID: 430157.
3)
Yoshida M, Watanabe M, Kuramoto S. “True” posterior communicating artery aneurysm. Surg Neurol. 1979;11:379–81.
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