Pain Treatment



Novel pain treatment methods such as the use of cannabinoids, stem cells, gene therapy, nanoparticles, monoclonal antibodies, and platelet-rich plasma have played a significant role in improved strategies for therapeutic interventions. Although many management options appear to be promising, extensive additional clinical research is warranted to determine best practice strategies in the future for clinicians 1).

Medication

see Pain medication.

see Pain surgery.

Pain treatment after aneurysmal subarachnoid hemorrhage


Pain management following major intracranial surgery is often limited by a presumed lack of need and a concern that opioid analgesics will adversely affect postoperative outcome and interfere with the neurologic examination. Nevertheless, evidence in adults is accumulating that these patients suffer moderate to severe pain, and this pain is often under-treated.


The anterior cingulate cortex (ACC) is a structure involved in the affective component, and targeting it may relieve patients' pain.

1)
Kataria S, Patel U, Yabut K, Patel J, Patel R, Patel S, Wijaya JH, Maniyar P, Karki Y, Makrani MP, Viswanath O, Kaye AD. Recent Advances in Management of Neuropathic, Nociceptive, and Chronic Pain: A Narrative Review with Focus on Nanomedicine, Gene Therapy, Stem Cell Therapy, and Newer Therapeutic Options. Curr Pain Headache Rep. 2024 Feb 22. doi: 10.1007/s11916-024-01227-5. Epub ahead of print. PMID: 38386244.