The first report of chemical neurolysis was made in 1863 by Luton who delivered irritant chemicals subcutaneously in patients with sciatica, offering them significant alleviation of pain 1).
In cases of ulnar nerve compression at the cubital tunnel, both neurolysis and transposition are effective in improving clinical outcome. The only statistically significant advantage of neurolysis over transposition seems to be relief of localized elbow pain. Kamat et al, recommend neurolysis as the preferred procedure 2).