Lateralization [Neurosurgery Wiki]

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====== Lateralization ======

The hemispheric [[dominance]] theory, or left brain versus right brain theory, proposes that each side (hemisphere) of the brain controls certain cognitive processes. The separation of functions between the sides of the [[brain]] is called [[lateralization]] or laterality.
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Mandonnet et al. reported a [[case series]] of four patients operated on for a [[glioma]] in [[awake]] conditions and in whom [[task-based functional magnetic resonance imaging]] (fMRI) demonstrated right-[[dominant]] activity during a [[language]] production [[task]]. Language [[functional]] sites were identified intraoperatively by [[electrical stimulation]]s only in the patient with a right-sided lesion. Furthermore, the pre- or postoperative [[cognitive]] evaluations in the three patients operated on for a left-sided [[glioma]] revealed right [[spatial neglect]] and [[dysexecutive syndrome]], hence demonstrating that, in patients with right-dominant activity on language fMRI, the left hemisphere is implicated in spatial [[consciousness]] and cognitive control. This study supports the interest of presurgical task-based language fMRI to identify patients with a reversed lateralization of [[cognitive function]]s and to make an adequate selection of the battery of intraoperative [[cognitive task]]s to be monitored in those rare outliers
((Mandonnet E, Mellerio C, Barberis M, Poisson I, Jansma JM, Rutten GJ. When
Right Is on the Left (and Vice Versa): A Case Series of Glioma Patients with
Reversed Lateralization of Cognitive Functions. J Neurol Surg A Cent Eur
Neurosurg. 2020 Feb 17. doi: 10.1055/s-0040-1701625. [Epub ahead of print] PubMed
PMID: 32066189.
)).