Show pageBacklinksCite current pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. =====Coumarin===== Coumarin was first synthesized in 1868. It is used in the pharmaceutical industry as a precursor reagent in the synthesis of a number of synthetic anticoagulant pharmaceuticals similar to dicoumarol, the notable ones being [[warfarin]] (brand name Coumadin) and some even more potent rodenticides that work by the same anticoagulant mechanism. So-called "coumarins" (modified coumarins) are a type of vitamin K antagonists. Pharmaceutical (modified) coumarins were all developed from the study of sweet clover disease; see warfarin for this history. However, unmodified coumarin itself, as it occurs in plants, has no effect on the vitamin K coagulation system, or on the action of warfarin-type drugs. coumarin.txt Last modified: 2024/06/07 02:49by 127.0.0.1