Breast cancer intracranial metastases epidemiology [Neurosurgery Wiki]

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====== Breast cancer intracranial metastases epidemiology ======

In adults, lung and breast Ca together account for > 50% of cerebral mets

[[Intracranial metastases]] commonly occurs in breast cancer and has been identified in about 20% to 24% of breast cancer patients
((De Ieso PB, Schick U, Rosenfelder N, Mohammed K, Ross GM. Breast cancer brain metastases: a 12 year review of treatment outcomes. Breast. 2015;24:426–433.))
((Rostami R, Mittal S, Rostami P, Tavassoli F, Jabbari B. Brain metastasis in breast cancer: a comprehensive literature review. J Neurooncol. 2016;127:407–414.)).

It is the 2nd commonest cause of [[intracranial metastases]] after [[lung cancer]]
((Barnholtz-Sloan JS, Sloan AE, Davis FG, Vigneau FD, Lai P, Sawaya RE. Incidence proportions of brain metastases in patients diagnosed (1973–2001) in the metropolitan detroit cancer surveillance system. J Clin Oncol. 2004;22(14):2865–2872. doi:10.1200/JCO.2004.12.149.)).

As patients with advanced breast cancer live longer due to improvements in systemic therapies, the incidence of brain metastases (BM) appears to be increasing 
((Frisk G, Svensson T, Backlund LM, Lidbrink E, Blomqvist P, Smedby KE. Incidence and time trends of brain metastases admissions among breast cancer patients in Sweden. Br J Cancer. 2012;106(11):1850–1853. doi:10.1038/bjc.2012.163.)).