One of the key metabolic alterations in cancer cells is the Warburg effect, which describes the increased glucose uptake and glycolysis that occurs in cancer cells, even in the presence of oxygen. This results in the production of lactate as a byproduct, which can further contribute to the acidification of the tumor microenvironment.

Like mosttumors, meningiomas prefer anaerobic glycolysis for energy production (Warburg effect).