Sinusitis complications

Brain abscesses caused by sinusitis are rare in the antibiotic era.

A rare case of a brain abscess located mainly in the frontal lobe after sinusitis, which was initially thought to be meningitis or encephalitis. A 39-year-old man was transferred to the hospital from another neighbouring hospital with tonic-clonic seizures, severe headache, and purulent nasal secretions. For one week, he was taking antibiotics for sinusitis. The computed tomography indicated lesions in the right sinuses but not in the parenchymal brain and thus antibiotics along with antiepileptic drugs were given. However, due to the deterioration of symptoms, magnetic resonance imaging was executed, which revealed an abscess in the frontal lobe. Afterward, an anterior ethmoidectomy and middle maxillary antrostomy were performed in order to drain the purulent content from the right sinuses. Ten days later, the patient presented disorientation and thus an open craniotomy for successful removal of the parenchymal abscess was performed. One month later, the patient was discharged with mild irritability, which was eliminated gradually over the next two months. Conclusively, brain abscesses can be caused by local spread from an infection of the paranasal sinus. The contribution of imaging modality is very significant not only for the early diagnosis but also for the therapeutic management of such cases. Frequently antibiotic treatment is insufficient and surgery may be required 2).

Twenty-one patients with intracranial sinogenic complications were treated at the Department of Otolaryngology in Poznan during that time.

Brain abscesses were the most common complications. Intracranial complications of sinusitis rarely occurred in isolation, often coexisting with other intracranial pathologies. A significant increase in the incidence was recorded in 2013. Treatment involved concurrently alleviating inflammation in the sinuses through implementation of broad-spectrum antibiotics for several weeks and decompressing the organized intracerebral abscesses, empyema, epidural and/or subdural abscesses under control of neuronavigation. There were no patient deaths recorded in the analyzed period. Conclusions The risk of developing intracranial sinogenic complications is low but invariably present and should be included in the differential diagnosis. Since the incidence of intracranial complications may increase in the course of prevailing viral infection, it should raise diagnostic vigilance 3).


1)
Sexton GP, Nae A, Cleere EF, O'Riordan I, O'Neill JP, Lacy PD, Amin M, Colreavy M, Caird J, Crimmins D. Concurrent management of suppurative intracranial complications of sinusitis and acute otitis media in children. Int J Pediatr Otorhinolaryngol. 2022 Mar 4;156:111093. doi: 10.1016/j.ijporl.2022.111093. Epub ahead of print. PMID: 35272257.
2)
Michali MC, Kastanioudakis IG, Basiari LV, Alexiou G, Komnos ID. Parenchymal Brain Abscess as an Intracranial Complication After Sinusitis. Cureus. 2021 Aug 22;13(8):e17365. doi: 10.7759/cureus.17365. PMID: 34567904; PMCID: PMC8454594.
3)
Szyfter W, Kruk-Zagajewska A, Bartochowska A, Borucki Ł. Intracranial complications from sinusitis. Otolaryngol Pol. 2015;69(3):6-14. doi: 10.5604/00306657.1156326. PubMed PMID: 26388244.
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