ReDura

From Medprin.

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ReDura™ is manufactured with FDA approved degradable material polylactic acid which has been widely proved the biocompatibility and non toxicity. It has been widely applied in more than 30 countries, and demonstrates outstanding efficacy and safety for the repair of the dural defect.

Redura™ is hydrophobic with more than 90 contact angle which acts as a watertight barrier for the prevention of cerebrospinal fluid (CSF) Leakage. It attains a favorable dural closure, preventing common complications associated with CSF Leakage.

Redura™ achieves excellent tensile strength, strong enough for positioning and repositioning of the product during operative handling. The biomaterial does not swell and can be easily unfolded after hydration without tearing.

Redura™ is flexible and conforms to the contours of the brain very well after hydration, limit the risk of foreign body reaction, and mitigate the possibility of immunological response.

The biomimetic structure of Redura™ resembles to the microstructure of native dural matrix, providing an appropriate trestle for cells proliferation, rapidly repairing the defective area.

With the advantage of thinness, softness and high strength, Redura TM is easy and simple to apply with flexibility.

The unique material property of Redura TM endows the product favourable anti-adhesion ability to surrounding tissues, which has been proved by low adheasion risk in tens of thousands of clinical cases.

Zenga et al., from the Division of Neurosurgery and 1st Division of ENT, Department of Surgical Sciences, University of Torino, Turin, presented in 2016 the experience with ReDura (Medprin Biotech, La Mirada, California, United States), as a subdural inlay in three patients who underwent endoscopic endonasal removal of sellar and suprasellar lesions.

ReDura patch showed the same versatility of autologous iliotibial tract. A dural patch that easily adapts to all defects, revealed to be a useful tool for performing watertight closure, possibly in a short operative time, after endoscopic approaches 1).


1)
Zenga F, Tardivo V, Pacca P, Garzaro M, Garbossa D, Ducati A. Nanofibrous Synthetic Dural Patch for Skull Base Defects: Preliminary Experience for Reconstruction after Extended Endonasal Approaches. J Neurol Surg Rep. 2016 Mar;77(1):e50-5. doi: 10.1055/s-0035-1570388. PubMed PMID: 26937335; PubMed Central PMCID: PMC4773823.
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