Platelet-to-lymphocyte ratio for mechanical thrombectomy outcome
The association with hemorrhagic change and the recovery parameters at the 24th hour may enable platelet-to-lymphocyte ratio (PLR) and Neutrophil to lymphocyte ratio to be used as significant prognostic factors in patients with acute ischemic stroke undergoing mechanical thrombectomy. Further studies are needed 1).
The platelet-to-lymphocyte ratio could represent pro-thrombotic inflammatory state in acute ischemic stroke patients because having a high-PLR values increased the poor prognosis, the rate of insufficient recanalization, and the size of infarcted area 2).
For Lee et al. Higher NLR and PLR were associated with unsuccessful reperfusion after EVT. The combined application of both biomarkers could be useful for predicting outcomes after EVT 3).
A study demonstrated that both NLR and PLR were independent predictors of 3-months functional outcomes of AIS. They may help to identify high-risk patients more forcefully when combined together 4).
In patients with mechanical thrombectomy (MT), platelet-to-lymphocyte ratio (PLR) and Neutrophil to lymphocyte ratio on admission could be predictive factors of prognosis and mortality at 3 months. Decreased PLR and increased Neutrophil to lymphocyte ratio were associated with favorable clinical outcome 3 months after MT 5).