Not to be confused with the infraorbital groove, infraorbital canal, and infraorbital foramen.

The lateral wall and the floor of the orbit are separated posteriorly by the inferior orbital fissure which transmits the zygomatic branch of the maxillary nerve, and the ascending branches from the pterygopalatine ganglion. The infraorbital vessels are found in the inferior orbital fissure, and travel down the infraorbital groove into the infraorbital canal and exit through the infraorbital foramen.

It is formed by the sphenoid bone and maxilla.

http://www.3dneuroanatomy.com/wp-content/uploads/2014/12/orb3.jpg