Icodextrin (INN, USAN) is a colloid osmotic agent, derived from maltodextrin, used in form of an aqueous solution for peritoneal dialysis under the trade name Extraneal, and after gynecological laparoscopic surgery for the reduction of post-surgical adhesions (fibrous bands that form between tissues and organs) under the trade name Adept.

The intraabdominal instillation of icodextrin, can decrease the rate of shunt dysfunction in a ventriculoperitoneal shunt by preventing formation of intraperitoneal fibrosis in a rat model 1).

see Sclerosing encapsulating peritonitis.


1)
Aydoseli A, Tahta A, Aras Y, Sabancı A, Keskin M, Balik E, Onder S, Sencer A, Izgi N. Use of Antifibrotics to Prevent Ventriculoperitoneal Shunt Complications Due to Intra-abdominal Fibrosis: Experimental Study in a Rat Model. J Neurol Surg A Cent Eur Neurosurg. 2015 Mar 26. [Epub ahead of print] PubMed PMID: 25811104.
  • icodextrin.txt
  • Last modified: 2024/06/07 02:49
  • by 127.0.0.1