Neurochirurgische Klinik und Poliklinik Universitätsklinikum Würzburg
Josef-Schneider-Straße 11
97080 Würzburg
Prof. Dr. med. Ralf-Ingo ERNESTUS Direktor Tel.: 0931/201-24800 Fax: 0931/201-24635 Ernestus_R@ukw.de
Conference president Prof. Dr. Ralf-Ingo Ernestus organize the 70th Annual Meeting of the German Society of Neurosurgery from May 12-15, 2019 in Würzburg.
Löhr M, Freitag B, Technau A, Krauss J, Monoranu CM, Rachor J, Lutz MB, Hagemann C, Kessler AF, Linsenmann T, Wölfl M, Ernestus RI, Engelhardt S, Gelbrich G, Schlegel PG, Eyrich M. High grade glioma associated immunosuppression does not prevent immune responses induced by therapeutic vaccines in combination with T(reg) depletion. Cancer Immunol Immunother. 2018 Jul 27. doi: 10.1007/s00262-018-2214-0. [Epub ahead of print] PubMed PMID: 30054667.
2: Kehrer-Sawatzki H, Kluwe L, Friedrich RE, Summerer A, Schäfer E, Wahlländer U, Matthies C, Gugel I, Farschtschi S, Hagel C, Cooper DN, Mautner VF. Phenotypic and genotypic overlap between mosaic NF2 and schwannomatosis in patients with multiple non-intradermal schwannomas. Hum Genet. 2018 Jul 13. doi: 10.1007/s00439-018-1909-9. [Epub ahead of print] PubMed PMID: 30006736.
3: Gröbner SN, Worst BC, Weischenfeldt J, Buchhalter I, Kleinheinz K, Rudneva VA, Johann PD, Balasubramanian GP, Segura-Wang M, Brabetz S, Bender S, Hutter B, Sturm D, Pfaff E, Hübschmann D, Zipprich G, Heinold M, Eils J, Lawerenz C, Erkek S, Lambo S, Waszak S, Blattmann C, Borkhardt A, Kuhlen M, Eggert A, Fulda S, Gessler M, Wegert J, Kappler R, Baumhoer D, Burdach S, Kirschner-Schwabe R, Kontny U, Kulozik AE, Lohmann D, Hettmer S, Eckert C, Bielack S, Nathrath M, Niemeyer C, Richter GH, Schulte J, Siebert R, Westermann F, Molenaar JJ, Vassal G, Witt H, Burkhardt B, Kratz CP, Witt O, van Tilburg CM, Kramm CM, Fleischhack G, Dirksen U, Rutkowski S, Frühwald M, von Hoff K, Wolf S, Klingebiel T, Koscielniak E, Landgraf P, Koster J, Resnick AC, Zhang J, Liu Y, Zhou X, Waanders AJ, Zwijnenburg DA, Raman P, Brors B, Weber UD, Northcott PA, Pajtler KW, Kool M, Piro RM, Korbel JO, Schlesner M, Eils R, Jones DTW, Lichter P, Chavez L, Zapatka M, Pfister SM; ICGC PedBrain-Seq Project; ICGC MMML-Seq Project. Author Correction: The landscape of genomic alterations across childhood cancers. Nature. 2018 Jul;559(7714):E10. doi: 10.1038/s41586-018-0167-2. PubMed PMID: 29875405.
4: Kirsch AD, Hassin-Baer S, Matthies C, Volkmann J, Steigerwald F. Anodic versus cathodic neurostimulation of the subthalamic nucleus: A randomized-controlled study of acute clinical effects. Parkinsonism Relat Disord. 2018 May 16. pii: S1353-8020(18)30245-1. doi: 10.1016/j.parkreldis.2018.05.015. [Epub ahead of print] PubMed PMID: 29784559.
5: Deng MY, Sill M, Chiang J, Schittenhelm J, Ebinger M, Schuhmann MU, Monoranu CM, Milde T, Wittmann A, Hartmann C, Sommer C, Paulus W, Gärtner J, Brück W, Rüdiger T, Leipold A, Jaunmuktane Z, Brandner S, Giangaspero F, Nozza P, Mora J, Morales la Madrid A, Cruz Martinez O, Hansford JR, Pietsch T, Tietze A, Hernáiz-Driever P, Stoler I, Capper D, Korshunov A, Ellison DW, von Deimling A, Pfister SM, Sahm F, Jones DTW. Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features. Acta Neuropathol. 2018 May 15. doi: 10.1007/s00401-018-1865-4. [Epub ahead of print] PubMed PMID: 29766299.
6: Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, Segura-Wang M, Weischenfeldt J, Rausch T, Mardin BR, Zhou X, Baciu C, Lawerenz C, Chan JA, Varlet P, Guerrini-Rousseau L, Fults DW, Grajkowska W, Hauser P, Jabado N, Ra YS, Zitterbart K, Shringarpure SS, De La Vega FM, Bustamante CD, Ng HK, Perry A, MacDonald TJ, Hernáiz Driever P, Bendel AE, Bowers DC, McCowage G, Chintagumpala MM, Cohn R, Hassall T, Fleischhack G, Eggen T, Wesenberg F, Feychting M, Lannering B, Schüz J, Johansen C, Andersen TV, Röösli M, Kuehni CE, Grotzer M, Kjaerheim K, Monoranu CM, Archer TC, Duke E, Pomeroy SL, Shelagh R, Frank S, Sumerauer D, Scheurlen W, Ryzhova MV, Milde T, Kratz CP, Samuel D, Zhang J, Solomon DA, Marra M, Eils R, Bartram CR, von Hoff K, Rutkowski S, Ramaswamy V, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Malkin D, Gajjar A, Korbel JO, Pfister SM. Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort. Lancet Oncol. 2018 Jun;19(6):785-798. doi: 10.1016/S1470-2045(18)30242-0. Epub 2018 May 9. PubMed PMID: 29753700; PubMed Central PMCID: PMC5984248.
7: Capper D, Engel NW, Stichel D, Lechner M, Glöss S, Schmid S, Koelsche C, Schrimpf D, Niesen J, Wefers AK, Jones DTW, Sill M, Weigert O, Ligon KL, Olar A, Koch A, Forster M, Moran S, Tirado OM, Sáinz-Jaspeado M, Mora J, Esteller M, Alonso J, Del Muro XG, Paulus W, Felsberg J, Reifenberger G, Glatzel M, Frank S, Monoranu CM, Lund VJ, von Deimling A, Pfister S, Buslei R, Ribbat-Idel J, Perner S, Gudziol V, Meinhardt M, Schüller U. DNA methylation-based reclassification of olfactory neuroblastoma. Acta Neuropathol. 2018 Aug;136(2):255-271. doi: 10.1007/s00401-018-1854-7. Epub 2018 May 5. PubMed PMID: 29730775.
8: Schulze M, Hutterer M, Sabo A, Hoja S, Lorenz J, Rothhammer-Hampl T, Herold-Mende C, Floßbach L, Monoranu C, Riemenschneider MJ. Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions. BMC Cancer. 2018 May 3;18(1):524. doi: 10.1186/s12885-018-4440-4. PubMed PMID: 29724193; PubMed Central PMCID: PMC5934884.
9: Mihovilovic MI, Kertels O, Hänscheid H, Löhr M, Monoranu CM, Kleinlein I, Samnick S, Kessler AF, Linsenmann T, Ernestus RI, Buck AK, Lapa C. O-(2-1).
Lee JY, Keep RF, Hua Y, Ernestus RI, Xi G. Deferoxamine reduces early brain injury following subarachnoid hemorrhage. Acta Neurochir Suppl. 2011;112:101-6. doi: 10.1007/978-3-7091-0661-7_18. PubMed PMID: 21691996.
198: Arnold H, Collmann H. Neurosurgery in Würzburg until World War II. J Neurol Surg A Cent Eur Neurosurg. 2012 Jan;73(1):38-45. doi: 10.1055/s-0032-1304503. Epub 2012 Feb 6. PubMed PMID: 21786222.
199: van Oorschot B, Schuler M, Simon A, Schleicher U, Geinitz H. Patterns of care and course of symptoms in palliative radiotherapy: a multicenter pilot study analysis. Strahlenther Onkol. 2011 Aug;187(8):461-6. doi: 10.1007/s00066-011-2231-9. Epub 2011 Jul 22. PubMed PMID: 21786111.
200: Westermaier T, Jauss A, Eriskat J, Kunze E, Roosen K. The temporal profile of cerebral blood flow and tissue metabolites indicates sustained metabolic depression after experimental subarachnoid hemorrhage in rats. Neurosurgery. 2011 Jan;68(1):223-9; discussion 229-30. doi: 10.1227/NEU.0b013e3181fe23c1. PubMed PMID: 21099709.
201: Hagemann C, Weigelin B, Schommer S, Schulze M, Al-Jomah N, Anacker J, Gerngras S, Kühnel S, Kessler AF, Polat B, Ernestus RI, Patel R, Vince GH. The cohesin-interacting protein, precocious dissociation of sisters 5A/sister chromatid cohesion protein 112, is up-regulated in human astrocytic tumors. Int J Mol Med. 2011 Jan;27(1):39-51. doi: 10.3892/ijmm.2010.551. Epub 2010 Nov 8. PubMed PMID: 21069257.
202: Hagemann C, Anacker J, Haas S, Riesner D, Schömig B, Ernestus RI, Vince GH. Comparative expression pattern of Matrix-Metalloproteinases in human glioblastoma cell-lines and primary cultures. BMC Res Notes. 2010 Nov 10;3:293. doi: 10.1186/1756-0500-3-293. PubMed PMID: 21067565; PubMed Central PMCID: PMC2996401.
203: Hagemann C, Said HM, Flentje M, Roosen K, Vince GH. Proteins involved in cell migration from glioblastoma neurospheres analyzed by overexpression and siRNA-mediated knock-down. Methods Mol Biol. 2010;650:129-43. doi: 10.1007/978-1-60761-769-3_11. PubMed PMID: 20686949.
204: Guckenberger M, Baier K, Polat B, Richter A, Krieger T, Wilbert J, Mueller G, Flentje M. Dose-response relationship for radiation-induced pneumonitis after pulmonary stereotactic body radiotherapy. Radiother Oncol. 2010 Oct;97(1):65-70. doi: 10.1016/j.radonc.2010.04.027. Epub 2010 Jun 3. PubMed PMID: 20605245.
205: Raslan F, Schwarz T, Meuth SG, Austinat M, Bader M, Renné T, Roosen K, Stoll G, Sirén AL, Kleinschnitz C. Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation. J Cereb Blood Flow Metab. 2010 Aug;30(8):1477-86. doi: 10.1038/jcbfm.2010.28. Epub 2010 Mar 3. PubMed PMID: 20197781; PubMed Central PMCID: PMC2949241.
206: Pinto NC, Pinto FC, Alho EJ, Yoshimura EM, Krebs VL, Teixeira MJ, Chavantes MC. Pilot study in neonates using low-level laser therapy in the immediate postoperative period of myelomeningocele. Einstein (Sao Paulo). 2010 Mar;8(1):5-9. doi: 10.1590/S1679-45082010AO1441. English, Portuguese. PubMed PMID: 26761745.
207: Byts N, Sirén AL. Erythropoietin: a multimodal neuroprotective agent. Exp Transl Stroke Med. 2009 Oct 21;1:4. doi: 10.1186/2040-7378-1-4. PubMed PMID: 20142991; PubMed Central PMCID: PMC2816866.
208: Aleksic I, Sommer SP, Kottenberg-Assenmacher E, Lange V, Schimmer C, Oezkur M, Leyh RG, Gorski A. Cardiac operations in the presence of meningioma. Ann Thorac Surg. 2009 Oct;88(4):1264-8. doi: 10.1016/j.athoracsur.2009.06.054. PubMed PMID: 19766819.
209: Rauch S, Kasuya Y, Turan A, Neamtu A, Vinayakan A, Sessler DI. Ultrasound-guided lumbar medial branch block in obese patients: a fluoroscopically confirmed clinical feasibility study. Reg Anesth Pain Med. 2009 Jul-Aug;34(4):340-2. PubMed PMID: 19585701.
210: Guckenberger M, Wilbert J, Krieger T, Richter A, Baier K, Flentje M. Mid-ventilation concept for mobile pulmonary tumors: internal tumor trajectory versus selective reconstruction of four-dimensional computed tomography frames based on external breathing motion. Int J Radiat Oncol Biol Phys. 2009 Jun 1;74(2):602-9. doi: 10.1016/j.ijrobp.2008.12.062. PubMed PMID: 19427559.
211: Westermaier T, Jauss A, Eriskat J, Kunze E, Roosen K. Time-course of cerebral perfusion and tissue oxygenation in the first 6 h after experimental subarachnoid hemorrhage in rats. J Cereb Blood Flow Metab. 2009 Apr;29(4):771-9. doi: 10.1038/jcbfm.2008.169. Epub 2009 Jan 21. PubMed PMID: 19156162.
212: Sirén AL, Fasshauer T, Bartels C, Ehrenreich H. Therapeutic potential of erythropoietin and its structural or functional variants in the nervous system. Neurotherapeutics. 2009 Jan;6(1):108-27. doi: 10.1016/j.nurt.2008.10.041. Review. PubMed PMID: 19110203; PubMed Central PMCID: PMC5084260.
213: Hagemann C, Gloger J, Anacker J, Said HM, Gerngras S, Kühnel S, Meyer C, Rapp UR, Kämmerer U, Vordermark D, Flentje M, Roosen K, Vince GH. RAF expression in human astrocytic tumors. Int J Mol Med. 2009 Jan;23(1):17-31. PubMed PMID: 19082503.
214: Westermaier T, Jauss A, Eriskat J, Kunze E, Roosen K. Acute vasoconstriction: decrease and recovery of cerebral blood flow after various intensities of experimental subarachnoid hemorrhage in rats. J Neurosurg. 2009 May;110(5):996-1002. doi: 10.3171/2008.8.JNS08591. PubMed PMID: 19061352.
215: Collmann H, Vitzthum HE. Historical perspective on neurosurgery in Germany after World War II. Neurosurgery. 2008 Nov;63(5):989-99; discussion 999-1000. doi: 10.1227/01.NEU.0000330411.81772.19. PubMed PMID: 19005391.
216: Collmann H, Mornet E, Gattenlöhner S, Beck C, Girschick H. Neurosurgical aspects of childhood hypophosphatasia. Childs Nerv Syst. 2009 Feb;25(2):217-23. doi: 10.1007/s00381-008-0708-3. Epub 2008 Sep 4. PubMed PMID: 18769927.
217: Hagemann C, Anacker J, Gerngras S, Kühnel S, Said HM, Patel R, Kämmerer U, Vordermark D, Roosen K, Vince GH. Expression analysis of the autosomal recessive primary microcephaly genes MCPH1 (microcephalin) and MCPH5 (ASPM, abnormal spindle-like, microcephaly associated) in human malignant gliomas. Oncol Rep. 2008 Aug;20(2):301-8. PubMed PMID: 18636190.
218: Byts N, Samoylenko A, Fasshauer T, Ivanisevic M, Hennighausen L, Ehrenreich H, Sirén AL. Essential role for Stat5 in the neurotrophic but not in the neuroprotective effect of erythropoietin. Cell Death Differ. 2008 Apr;15(4):783-92. doi: 10.1038/cdd.2008.1. Epub 2008 Feb 8. PubMed PMID: 18259195.
219: Samoylenko A, Byts N, Rajalingam K, von Ahsen N, Rapp UR, Ehrenreich H, Sirén AL. Thrombopoietin inhibits nerve growth factor-induced neuronal differentiation and ERK signalling. Cell Signal. 2008 Jan;20(1):154-62. Epub 2007 Oct 12. PubMed PMID: 18006272.
220: Stojic J, Hagemann C, Haas S, Herbold C, Kühnel S, Gerngras S, Roggendorf W, Roosen K, Vince GH. Expression of matrix metalloproteinases MMP-1, MMP-11 and MMP-19 is correlated with the WHO-grading of human malignant gliomas. Neurosci Res. 2008 Jan;60(1):40-9. Epub 2007 Sep 29. PubMed PMID: 17980449.
221: Wiese S, Jablonka S, Holtmann B, Orel N, Rajagopal R, Chao MV, Sendtner M. Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17210-5. Epub 2007 Oct 16. PubMed PMID: 17940030; PubMed Central PMCID: PMC2040418.
222: Westermaier T, Eriskat J, Kunze E, Günthner-Lengsfeld T, Vince GH, Roosen K. Clinical features, treatment, and prognosis of patients with acute subdural hematomas presenting in critical condition. Neurosurgery. 2007 Sep;61(3):482-7; discussion 487-8. PubMed PMID: 17881959.
223: Schlegel N, Asan E, Hofmann GO, Lang EM. Reactive changes in dorsal roots and dorsal root ganglia after C7 dorsal rhizotomy and ventral root avulsion/replantation in rabbits. J Anat. 2007 Mar;210(3):336-51. PubMed PMID: 17331182; PubMed Central PMCID: PMC2100279.
224: Uçeyler N, Tscharke A, Sommer C. Early cytokine expression in mouse sciatic nerve after chronic constriction nerve injury depends on calpain. Brain Behav Immun. 2007 Jul;21(5):553-60. Epub 2007 Jan 3. PubMed PMID: 17204395.
225: Vordermark D, Ruprecht K, Rieckmann P, Roggendorf W, Vince GH, Warmuth-Metz M, Kölbl O, Flentje M. Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26). BMC Cancer. 2006 Oct 18;6:247. PubMed PMID: 17049083; PubMed Central PMCID: PMC1621074.
226: Felbor U, Sure U, Grimm T, Bertalanffy H. Genetics of cerebral cavernous angioma. Zentralbl Neurochir. 2006 Aug;67(3):110-6. Review. PubMed PMID: 16958007.
227: Rosenow DE, Frowein R, Dietz H. Erich Fischer-brügge (28.12.1904-4.2.1951) – founder of neurosurgery at the university of Münster. Zentralbl Neurochir. 2006 May;67(2):88-92; discussion 93. PubMed PMID: 16673241.
228: Hagemann C, Meyer C, Stojic J, Eicker S, Gerngras S, Kühnel S, Roosen K, Vince GH. High efficiency transfection of glioma cell lines and primary cells for overexpression and RNAi experiments. J Neurosci Methods. 2006 Sep 30;156(1-2):194-202. Epub 2006 Apr 18. PubMed PMID: 16621008.
229: Wessig C, Kenn W, Koltzenburg M, Bendszus M. Denervation hypertrophy may mimic local tumor spread on magnetic resonance imaging. Muscle Nerve. 2006 Jul;34(1):108-10. PubMed PMID: 16583365.
230: Schropp C, Sörensen N, Krauss J. Early periinsular hemispherotomy in children with Sturge-Weber syndrome and intractable epilepsy–outcome in eight patients. Neuropediatrics. 2006 Feb;37(1):26-31. PubMed PMID: 16541365.
231: Schwemmer U, Schleppers A, Markus C, Kredel M, Kirschner S, Roewer N. [Operative management in axillary brachial plexus blocks: comparison of ultrasound and nerve stimulation]. Anaesthesist. 2006 Apr;55(4):451-6. German. PubMed PMID: 16463076.
232: Nolte I, Vince GH, Maurer M, Herbold C, Goldbrunner R, Solymosi L, Stoll G, Bendszus M. Iron particles enhance visualization of experimental gliomas with high-resolution sonography. AJNR Am J Neuroradiol. 2005 Jun-Jul;26(6):1469-74. PubMed PMID: 15956517.
233: Vordermark D, Kölbl O, Ruprecht K, Vince GH, Bratengeier K, Flentje M. Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma. BMC Cancer. 2005 May 30;5:55. PubMed PMID: 15924621; PubMed Central PMCID: PMC1156875.
234: Kleinschnitz C, Brinkhoff J, Sommer C, Stoll G. Contralateral cytokine gene induction after peripheral nerve lesions: dependence on the mode of injury and NMDA receptor signaling. Brain Res Mol Brain Res. 2005 May 20;136(1-2):23-8. PubMed PMID: 15893583.
235: Collmann H, Sörensen N, Krauss J. Hydrocephalus in craniosynostosis: a review. Childs Nerv Syst. 2005 Oct;21(10):902-12. Epub 2005 Apr 27. Review. PubMed PMID: 15864600.
236: Schwemmer U, Markus CK, Greim CA, Brederlau J, Roewer N. Ultrasound-guided anaesthesia of the axillary brachial plexus: efficacy of multiple injection approach. Ultraschall Med. 2005 Apr;26(2):114-9. PubMed PMID: 15852174.
237: Bendszus M, Wessig C, Schütz A, Horn T, Kleinschnitz C, Sommer C, Misselwitz B, Stoll G. Assessment of nerve degeneration by gadofluorine M-enhanced magnetic resonance imaging. Ann Neurol. 2005 Mar;57(3):388-95. PubMed PMID: 15732113.
238: Woydt M, Kripfgans OD, Fowlkes BJ, Roosen K, Carson PL. Functional imaging with intraoperative ultrasound: detection of somatosensory cortex in dogs with color-duplex sonography. Neurosurgery. 2005 Feb;56(2):355-63; discussion 355-63. PubMed PMID: 15670383.
239: George A, Buehl A, Sommer C. Wallerian degeneration after crush injury of rat sciatic nerve increases endo- and epineurial tumor necrosis factor-alpha protein. Neurosci Lett. 2004 Dec 6;372(3):215-9. PubMed PMID: 15542243.
240: George A, Kleinschnitz C, Zelenka M, Brinkhoff J, Stoll G, Sommer C. Wallerian degeneration after crush or chronic constriction injury of rodent sciatic nerve is associated with a depletion of endoneurial interleukin-10 protein. Exp Neurol. 2004 Jul;188(1):187-91. PubMed PMID: 15191815.
241: Bendszus M, Wessig C, Solymosi L, Reiners K, Koltzenburg M. MRI of peripheral nerve degeneration and regeneration: correlation with electrophysiology and histology. Exp Neurol. 2004 Jul;188(1):171-7. PubMed PMID: 15191813.
242: Wendt TG, Gademann G, Pambor C, Grießbach I, von Specht H, Martin T, Baltas D, Kurek R, Röddiger S, Tunn UW, Zamboglou N, Eich HT, Staar S, Gossmann A, Hansemann K, Semrau R, Skripnitchenko R, Diehl V, Müller RP, Sehlen S, Willich N, Rühl U, Lukas P, Dühmke E, Engel K, Tabbert E, Bolck M, Knaack S, Annweiler H, Krempien R, Hoppe H, Harms W, Daeuber S, Schorr O, Treiber M, Debus J, Alber M, Paulsen F, Birkner M, Bakai A, Belka C, Budach W, Grosser KH, Kramer R, Kober B, Reinert M, Schneider P, Hertel A, Feldmann H, Csere P, Hoinkis C, Rothe G, Zahn P, Alheit H, Cavanaugh SX, Kupelian P, Reddy C, Pollock B, Fuss M, Roeddiger S, Dannenberg T, Rogge B, Drechsler D, Herrmann T, Alberti W, Schwarz R, Graefen M, Krüll A, Rudat V, Huland H, Fehr C, Baum C, Glocker S, Nüsslin F, Heil T, Lemnitzer H, Knips M, Baumgart O, Thiem W, Kloetzer KH, Hoffmann L, Neu B, Hültenschmidt B, Sautter-Bihl ML, Micke O, Seegenschmiedt MH, Köppen D, Klautke G, Fietkau R, Schultze J, Schlichting G, Koltze H, 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Eßer D, Göbel H, Wördehoff H, Pachmann S, Hollenhorst H, Dederer K, Evers C, Lamprecht J, Dastbaz A, Schick B, Fleckenstein J, Plinkert PK, Rübe C, Merz T, Sommer B, Mencl A, Ghilescu V, Astner S, Martin A, Momm F, Volegova-Neher NJ, Schulte-Mönting J, Guttenberger R, Buchali A, Blank E, Sidow D, Huhnt W, Gorbatov T, Heinecke A, Beckmann G, Bentia AM, Schmitz H, Spahn U, Heyl V, Prott PJ, Galalae R, Schneider R, Voith C, Scheda A, Hermann B, Bauer L, Melchert F, Kröger N, Grüneisen A, Jänicke F, Zander A, Zuna I, Schlöcker I, Wagner K, John E, Dörk T, Lochhas G, Houf M, Lorenz D, Link KH, Prott FJ, Thoma M, Schauer R, Heinemann V, Romano M, Reiner M, Quanz A, Oppitz U, Bahrehmand R, Tine M, Naszaly A, Patonay P, Mayer Á, Markert K, Mai SK, Lohr F, Dobler B, Pinkawa M, Fischedick K, Treusacher P, Cengiz D, Mager R, Borchers H, Jakse G, Eble MJ, Asadpour B, Krenkel B, Holy R, Kaplan Y, Block T, Czempiel H, Haverkamp U, Prümer B, Christian T, Benkel P, Weber C, Gruber S, Reimann P, 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243: Bischofs S, Zelenka M, Sommer C. Evaluation of topiramate as an anti-hyperalgesic and neuroprotective agent in the peripheral nervous system. J Peripher Nerv Syst. 2004 Jun;9(2):70-8. PubMed PMID: 15104694.
244: Collmann H, Rosenow DE. [Pioneers of neurosurgery: Emil Heymann (4/15/1878-1/11/1936)]. Zentralbl Neurochir. 2004;65(1):36-9. German. PubMed PMID: 15046016.
245: Molle KD, Chédotal A, Rao Y, Lumsden A, Wizenmann A. Local inhibition guides the trajectory of early longitudinal tracts in the developing chick brain. Mech Dev. 2004 Feb;121(2):143-56. PubMed PMID: 15037316.
246: Wulf J, Hädinger U, Oppitz U, Thiele W, Flentje M. Stereotactic boost irradiation for targets in the abdomen and pelvis. Radiother Oncol. 2004 Jan;70(1):31-6. PubMed PMID: 15036849.
247: Kleinschnitz C, Brinkhoff J, Zelenka M, Sommer C, Stoll G. The extent of cytokine induction in peripheral nerve lesions depends on the mode of injury and NMDA receptor signaling. J Neuroimmunol. 2004 Apr;149(1-2):77-83. PubMed PMID: 15020067.
248: Stoll G, Schroeter M, Jander S, Siebert H, Wollrath A, Kleinschnitz C, Brück W. Lesion-associated expression of transforming growth factor-beta-2 in the rat nervous system: evidence for down-regulating the phagocytic activity of microglia and macrophages. Brain Pathol. 2004 Jan;14(1):51-8. PubMed PMID: 14997937.
249: Warmuth-Metz M, Kühl J, Krauss J, Solymosi L. Subdural enhancement on postoperative spinal MRI after resection of posterior cranial fossa tumours. Neuroradiology. 2004 Mar;46(3):219-23. Epub 2004 Feb 26. PubMed PMID: 14991260.
250: Wessig C, Koltzenburg M, Reiners K, Solymosi L, Bendszus M. Muscle magnetic resonance imaging of denervation and reinnervation: correlation with electrophysiology and histology. Exp Neurol. 2004 Feb;185(2):254-61. PubMed PMID: 14736506.
251: Hund M, Rickert S, Kinkelin I, Naumann M, Hamm H. Does wrist nerve block influence the result of botulinum toxin A treatment in palmar hyperhidrosis? J Am Acad Dermatol. 2004 Jan;50(1):61-2. PubMed PMID: 14699366.
252: Bendszus M, Stoll G. Caught in the act: in vivo mapping of macrophage infiltration in nerve injury by magnetic resonance imaging. J Neurosci. 2003 Nov 26;23(34):10892-6. PubMed PMID: 14645484.
253: Wendland JR, Schmidt KH, Koltzenburg M, Petersen M. No overlap of sensitivity to capsaicin and expression of galanin in rat dorsal root ganglion neurons after axotomy. Exp Brain Res. 2003 Nov;153(1):1-6. Epub 2003 Aug 29. PubMed PMID: 12955388.
254: Bendszus M, Müllges W, Goldbrunner R, Weigand A, Solymosi L. Hemodynamic effects of decompressive craniotomy in MCA infarction: evaluation with perfusion CT. Eur Radiol. 2003 Aug;13(8):1895-8. Epub 2002 Oct 12. PubMed PMID: 12942290.
255: Wulf J, Hädinger U, Oppitz U, Thiele W, Flentje M. Impact of target reproducibility on tumor dose in stereotactic radiotherapy of targets in the lung and liver. Radiother Oncol. 2003 Feb;66(2):141-50. PubMed PMID: 12648785.
256: Schäfers M, Geis C, Svensson CI, Luo ZD, Sommer C. Selective increase of tumour necrosis factor-alpha in injured and spared myelinated primary afferents after chronic constrictive injury of rat sciatic nerve. Eur J Neurosci. 2003 Feb;17(4):791-804. PubMed PMID: 12603269.
257: Gerlach M, Braak H, Hartmann A, Jost WH, Odin P, Priller J, Schwarz J. Current state of stem cell research for the treatment of Parkinson's disease. J Neurol. 2002 Oct;249 Suppl 3:III/33-5. Review. PubMed PMID: 12522570.
258: Burger R, Bendszus M, Vince GH, Roosen K, Marmarou A. A new reproducible model of an epidural mass lesion in rodents. Part I: Characterization by neurophysiological monitoring, magnetic resonance imaging, and histopathological analysis. J Neurosurg. 2002 Dec;97(6):1410-8. PubMed PMID: 12507141.
259: Bendszus M, Koltzenburg M, Wessig C, Solymosi L. Sequential MR imaging of denervated muscle: experimental study. AJNR Am J Neuroradiol. 2002 Sep;23(8):1427-31. PubMed PMID: 12223392.
260: Väth A, Kunze E, Roosen K, Meixensberger J. Therapeutic aspects of brain tissue pO2 monitoring after subarachnoid hemorrhage. Acta Neurochir Suppl. 2002;81:307-9. PubMed PMID: 12168333.
261: Mennel HD. [Klaus Joachim Zülch: Partner to neurosurgery, advocate of neurology and the neuropathological basis]. Zentralbl Neurochir. 2002;63(1):29-35. German. PubMed PMID: 12098081.
262: Naumann M, Hamm H. Treatment of axillary hyperhidrosis. Br J Surg. 2002 Mar;89(3):259-61. PubMed PMID: 11872047.
263: Poimann H. How can the ISO 9000 concept be applied to neurosurgery? Acta Neurochir Suppl. 2001;78:197-200. PubMed PMID: 11840720.
264: Schweizer U, Gunnersen J, Karch C, Wiese S, Holtmann B, Takeda K, Akira S, Sendtner M. Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult. J Cell Biol. 2002 Jan 21;156(2):287-97. Epub 2002 Jan 21. PubMed PMID: 11807093; PubMed Central PMCID: PMC2199226.
265: Samsam M, Frei R, Marziniak M, Martini R, Sommer C. Impaired sensory function in heterozygous P0 knockout mice is associated with nodal changes in sensory nerves. J Neurosci Res. 2002 Jan 15;67(2):167-73. PubMed PMID: 11782960.
266: Meixensberger J, Kunze E, Barcsay E, Vaeth A, Roosen K. Clinical cerebral microdialysis: brain metabolism and brain tissue oxygenation after acute brain injury. Neurol Res. 2001 Dec;23(8):801-6. PubMed PMID: 11760869.
267: Bendszus M, Koltzenburg M. Visualization of denervated muscle by gadolinium-enhanced MRI. Neurology. 2001 Nov 13;57(9):1709-11. PubMed PMID: 11706118.
268: Hüttmann S, Krauss J, Collmann H, Sörensen N, Roosen K. Surgical management of tethered spinal cord in adults: report of 54 cases. J Neurosurg. 2001 Oct;95(2 Suppl):173-8. PubMed PMID: 11599833.
269: Schlake HP, Goldbrunner RH, Milewski C, Krauss J, Trautner H, Behr R, Sörensen N, Helms J, Roosen K. Intra-operative electromyographic monitoring of the lower cranial motor nerves (LCN IX-XII) in skull base surgery. Clin Neurol Neurosurg. 2001 Jul;103(2):72-82. PubMed PMID: 11516548.
270: Schlake HP, Goldbrunner R, Siebert M, Behr R, Roosen K. Intra-Operative electromyographic monitoring of extra-ocular motor nerves (Nn. III, VI) in skull base surgery. Acta Neurochir (Wien). 2001;143(3):251-61. PubMed PMID: 11460913.
271: Väth A, Meixensberger J, Dings J, Roosen K. Advanced neuromonitoring including cerebral tissue oxygenation and outcome after traumatic brain injury. Neurol Res. 2001 Jun;23(4):315-20. PubMed PMID: 11428507.
272: Müller-Scholden J, Lehrnbecher T, Müller HL, Bensch J, Hengen RH, Sörensen N, Stockhausen HB. Radical surgery in a neonate with craniopharyngioma. report of a case. Pediatr Neurosurg. 2000 Nov;33(5):265-269. PubMed PMID: 11155065.
273: Bendszus M, Rao G, Burger R, Schaller C, Scheinemann K, Warmuth-Metz M, Hofmann E, Schramm J, Roosen K, Solymosi L. Is there a benefit of preoperative meningioma embolization? Neurosurgery. 2000 Dec;47(6):1306-11; discussion 1311-2. PubMed PMID: 11126901.
274: Lindenlaub T, Sommer C. Partial sciatic nerve transection as a model of neuropathic pain: a qualitative and quantitative neuropathological study. Pain. 2000 Dec 15;89(1):97-106. PubMed PMID: 11113298.
275: Wulf J, Hädinger U, Oppitz U, Olshausen B, Flentje M. Stereotactic radiotherapy of extracranial targets: CT-simulation and accuracy of treatment in the stereotactic body frame. Radiother Oncol. 2000 Nov;57(2):225-36. PubMed PMID: 11054527.
276: Ziebuhr W, Dietrich K, Trautmann M, Wilhelm M. Chromosomal rearrangements affecting biofilm production and antibiotic resistance in a Staphylococcus epidermidis strain causing shunt-associated ventriculitis. Int J Med Microbiol. 2000 Mar;290(1):115-20. PubMed PMID: 11043988.
277: Goldbrunner RH, Bendszus M, Sasaki M, Kraemer T, Plate KH, Roosen K, Tonn JC. Vascular endothelial growth factor-driven glioma growth and vascularization in an orthotopic rat model monitored by magnetic resonance imaging. Neurosurgery. 2000 Oct;47(4):921-9; discussion 929-30. PubMed PMID: 11014432.
278: Büchner K, Meixensberger J, Dings J, Roosen K. Near-infrared spectroscopy–not useful to monitor cerebral oxygenation after severe brain injury. Zentralbl Neurochir. 2000;61(2):69-73. PubMed PMID: 10986754.
279: Bouterfa HL, Sattelmeyer V, Czub S, Vordermark D, Roosen K, Tonn JC. Inhibition of Ras farnesylation by lovastatin leads to downregulation of proliferation and migration in primary cultured human glioblastoma cells. Anticancer Res. 2000 Jul-Aug;20(4):2761-71. PubMed PMID: 10953355.
280: Uemura K, Behr R, Roosen K. Symptomatic intraspinal air entrapment. Br J Neurosurg. 2000 Apr;14(2):154-6. PubMed PMID: 10889894.
281: Väth A, Meixensberger J, Dings J, Meinhardt M, Roosen K. Prognostic significance of advanced neuromonitoring after traumatic brain injury using neural networks. Zentralbl Neurochir. 2000;61(1):2-6. PubMed PMID: 10859794.
282: Lindenlaub T, Teuteberg P, Hartung T, Sommer C. Effects of neutralizing antibodies to TNF-alpha on pain-related behavior and nerve regeneration in mice with chronic constriction injury. Brain Res. 2000 Jun 2;866(1-2):15-22. PubMed PMID: 10825476.
283: Goldbrunner RH, Schlake HP, Milewski C, Tonn JC, Helms J, Roosen K. Quantitative parameters of intraoperative electromyography predict facial nerve outcomes for vestibular schwannoma surgery. Neurosurgery. 2000 May;46(5):1140-6; discussion 1146-8. PubMed PMID: 10807246.
284: Bendszus M, Warmuth-Metz M, Klein R, Burger R, Schichor C, Tonn JC, Solymosi L. MR spectroscopy in gliomatosis cerebri. AJNR Am J Neuroradiol. 2000 Feb;21(2):375-80. PubMed PMID: 10696026.
285: Bouterfa H, Picht T, Kess D, Herbold C, Noll E, Black PM, Roosen K, Tonn JC. Retinoids inhibit human glioma cell proliferation and migration in primary cell cultures but not in established cell lines. Neurosurgery. 2000 Feb;46(2):419-30. PubMed PMID: 10690732.
286: Bouterfa H, Darlapp AR, Klein E, Pietsch T, Roosen K, Tonn JC. Expression of different extracellular matrix components in human brain tumor and melanoma cells in respect to variant culture conditions. J Neurooncol. 1999 Aug;44(1):23-33. PubMed PMID: 10582665.
287: Tonn J, Hoffmann O, Hofmann E, Schlake HP, Sörensen N, Roosen K. “De novo” formation of intracranial aneurysms: who is at risk? Neuroradiology. 1999 Sep;41(9):674-9. PubMed PMID: 10525770.
288: Wiese S, Metzger F, Holtmann B, Sendtner M. Mechanical and excitotoxic lesion of motoneurons: effects of neurotrophins and ciliary neurotrophic factor on survival and regeneration. Acta Neurochir Suppl. 1999;73:31-9. Review. PubMed PMID: 10494338.
289: Frei R, Mötzing S, Kinkelin I, Schachner M, Koltzenburg M, Martini R. Loss of distal axons and sensory Merkel cells and features indicative of muscle denervation in hindlimbs of P0-deficient mice. J Neurosci. 1999 Jul 15;19(14):6058-67. PubMed PMID: 10407042.
290: Wagner S, Czub S, Greif M, Vince GH, Süss N, Kerkau S, Rieckmann P, Roggendorf W, Roosen K, Tonn JC. Microglial/macrophage expression of interleukin 10 in human glioblastomas. Int J Cancer. 1999 Jul 2;82(1):12-6. PubMed PMID: 10360813.
291: Wiese S, Metzger F, Holtmann B, Sendtner M. The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons. Eur J Neurosci. 1999 May;11(5):1668-76. PubMed PMID: 10215920.
292: Goldbrunner RH, Bernstein JJ, Tonn JC. Cell-extracellular matrix interaction in glioma invasion. Acta Neurochir (Wien). 1999;141(3):295-305; discussion 304-5. Review. PubMed PMID: 10214487.
293: Woydt M, Horowski A, Krone A, Soerensen N, Roosen K. Localization and characterization of intracerebral cavernous angiomas by intra-operative high-resolution colour-duplex-sonography. Acta Neurochir (Wien). 1999;141(2):143-51; discussion 152. PubMed PMID: 10189495.
294: Becker G, Hofmann E, Woydt M, Hülsmann U, Mäurer M, Lindner A, Becker T, Krone A. Postoperative neuroimaging of high-grade gliomas: comparison of transcranial sonography, magnetic resonance imaging, and computed tomography. Neurosurgery. 1999 Mar;44(3):469-77; discussion 477-8. PubMed PMID: 10069583.
295: Bendszus M, Sörensen N, Hofmann E, Röll E, Solymosi L. Fusiform dilatations of the internal carotid artery following surgery for pediatric suprasellar tumors. Pediatr Neurosurg. 1998 Dec;29(6):304-8. PubMed PMID: 9973677.
296: Klepper J, Büsse M, Strassburg HM, Sörensen N. Epilepsy in shunt-treated hydrocephalus. Dev Med Child Neurol. 1998 Nov;40(11):731-6. PubMed PMID: 9881801.
297: Goldbrunner RH, Bernstein JJ, Tonn JC. ECM-mediated glioma cell invasion. Microsc Res Tech. 1998 Nov 1;43(3):250-7. Review. PubMed PMID: 9840803.
298: Dings J, Meixensberger J, Jäger A, Roosen K. Clinical experience with 118 brain tissue oxygen partial pressure catheter probes. Neurosurgery. 1998 Nov;43(5):1082-95. PubMed PMID: 9802852.
299: Meixensberger J, Jäger A, Dings J, Baunach S, Roosen K. Multimodal hemodynamic neuromonitoring–quality and consequences for therapy of severely head injured patients. Acta Neurochir Suppl. 1998;71:260-2. PubMed PMID: 9779201.
300: Baunach S, Meixensberger J, Gerlach M, Lan J, Roosen K. Intraoperative microdialysis and tissue-pO2 measurement in human glioma. Acta Neurochir Suppl. 1998;71:241-3. PubMed PMID: 9779195.
301: Burger R, Vince GH, Meixensberger J, Roosen K. Bilateral monitoring of CBF and tissue oxygen pressure in the penumbra of a focal mass lesion in rats. Acta Neurochir Suppl. 1998;71:157-61. PubMed PMID: 9779172.
302: Kunze E, Meixensberger J, Janka M, Sörensen N, Roosen K. Decompressive craniectomy in patients with uncontrollable intracranial hypertension. Acta Neurochir Suppl. 1998;71:16-8. PubMed PMID: 9779131.
303: Berweiler U, Krone A, Tonn JC. Reservoir systems for intraventricular chemotherapy. J Neurooncol. 1998 Jun-Jul;38(2-3):141-3. Review. PubMed PMID: 9696364.
304: Burger R, Vince H, Meixensberger J, Roosen K. Hypothermia influences time course of intracranial pressure, brain temperature, EEG and microcirculation during ischemia-reperfusion. Neurol Res. 1998;20 Suppl 1:S52-60. PubMed PMID: 9584926.
305: Bouterfa H, Janka M, Meese E, Kerkau S, Roosen K, Tonn JC. Effect of changes in the CD44 gene on tumour cell invasion in gliomas. Neuropathol Appl Neurobiol. 1997 Oct;23(5):373-9. PubMed PMID: 9364462.
306: Tonn JC, Ott MM, Bouterfa H, Kerkau S, Kapp M, Müller-Hermelink HK, Roosen K. Inverse correlation of cell proliferation and expression of progesterone receptors in tumor spheroids and monolayer cultures of human meningiomas. Neurosurgery. 1997 Nov;41(5):1152-9. PubMed PMID: 9361071.
307: Vince GH, Bouterfa H, Goldbrunner R, Roosen K, Tonn JC. Fast blue, a fluorescent tracer in glioma cell culture, affects cell proliferation and motility. Neurosci Lett. 1997 Sep 19;233(2-3):148-50. PubMed PMID: 9350854.
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