USP8 (Ubiquitin Specific Peptidase 8) is a Protein Coding gene. Diseases associated with USP8 include pituitary neuroendocrine tumor, Acth-Secreting and Autosomal Recessive Spastic Paraplegia Type. Among its related pathways are Metabolism of proteins and EGF/EGFR Signaling Pathway. Gene Ontology (GO) annotations related to this gene include SH3 domain binding and thiol-dependent ubiquitin-specific protease activity.