Trigeminal neuralgia

• Second-line pharmacological treatment strategies for trigeminal neuralgia: A retrospective comparison of lacosamide, gabapentin and baclofen
• Factors Affecting Long-Term Pain Control After Gamma Knife Radiosurgery in Secondary Tumor-Related Trigeminal Neuralgia
• Trigeminal Semilunar Ganglion Stimulation Modulates Default Mode Network Connectivity in Trigeminal Neuralgia
• Long-term outcomes of peripheral nerve field stimulation in patients with refractory trigeminal neuralgia: a cohort study
• Which surgical technique has a superior clinical outcome in microvascular decompression? a systematic review and meta-analysis study of transposition versus interposition for trigeminal neuralgia and hemifacial spasm
• Outcomes and safety of repeated microvascular decompression for recurrent trigeminal neuralgia
• Application of neurite orientation dispersion and density imaging in characterizing brain microstructural changes in classical trigeminal neuralgia and a comparison between the left and right sides
• Enhanced Pain Relief with Guanfacine as an Adjuvant for Trigeminal Nerve Blocks: Insights from a PheWAS-Guided Randomized Controlled Study

The first adequate description of trigeminal neuralgia was given in 1671, followed by a fuller description by physician John Locke in 1677. André described the convulsive-like condition in 1756, and named it tic douloureux; in 1773, Fothergill described it as “a painful affection of the face;” and in 1779, John Hunter more clearly characterized the entity as a form of “nervous disorder” with reference to pain of the teeth, gums, or tongue where the disease “does not reside.” One hundred fifty years later, the neurological surgeon Walter Dandy equated neurovascular compression of the trigeminal nerve with trigeminal neuralgia. ^{1) 2)}

Trigeminal neuralgia definition.

see Trigeminal neuralgia epidemiology.

see Trigeminal neuralgia classification.

see Trigeminal neuralgia pathogenesis.

see Trigeminal neuralgia pathophysiology.

Typical trigeminal neuralgia caused by microvascular compression of the trigeminal nerve root in the posterior fossa may become transformed over time into atypical trigeminal neuralgia, if left untreated. This transformation involves change in the character of pain and development of sensory impairment. Two representative cases are presented to support this theory.

If the theory of progressive change in character of pain and degree of sensory impairment in the course of otherwise typical trigeminal neuralgia is correct, trigeminal neuralgia, atypical neuralgia, and trigeminal neuropathic pain may represent different degrees of injury to the trigeminal nerve, therefore comprising a continuous spectrum rather than discrete diagnoses ³⁾.

Trigeminal neuralgia clinical features.

Barrow Neurological Institute Pain Scale.

Barrow Neurological Facial Numbness Scale.

Slavin KV. Commentary: Development and Evaluation of a Preoperative Trigeminal Neuralgia Scoring System to Predict Long-Term Outcome Following Microvascular Decompression. Neurosurgery. 2019 Dec 9. pii: nyz540. doi: 10.1093/neuros/nyz540. [Epub ahead of print] PubMed PMID: 31813971.

Trigeminal neuralgia diagnosis.

see Trigeminal neuralgia treatment.

see Trigeminal neuralgia outcome.

see Trigeminal neuralgia case series.

see Trigeminal neuralgia case reports.