Transforming growth factor beta 1

Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. In humans, TGF-β1 is encoded by the TGFB1 gene.

Silencing of FoxM1 could reverse TGF-β1-induced invasion and epithelial-mesenchymal transition (EMT) of endometriotic epithelial cells (EECs) 1).

1)
Zhang J, Xu Z, Dai H, Zhao J, Liu T, Zhang G. Silencing of Forkhead Box M1 Reverses Transforming Growth Factor-β1-Induced Invasion and Epithelial-Mesenchymal Transition of Endometriotic Epithelial Cells. Gynecol Obstet Invest. 2019 Apr 30:1-10. doi: 10.1159/000499625. [Epub ahead of print] PubMed PMID: 31039568.