Anticholinergics may negatively impact cognition and memory 1) 2). Newer agents (tolterodine, darifenacin) have less impact on memory. Trospium, a quaternary amine, crosses the blood-brain barrier less readily than other anticholinergics and may have a less negative impact 3).

1)
Moga DC, Carnahan RM, Lund BC, et al. Risks and benefits of bladder antimuscarinics among elderly residents of Veterans Affairs Community Living Centers. J Am Med Dir Assoc. 2013; 14:749–760
2) , 3)
Kay GG, Ebinger U. Preserving cognitive function for patients with overactive bladder: evidence for a dif- ferential effect with darifenacin. Int J Clin Pract. 2008; 62:1792–1800