Dysembryoplastic Neuroepithelial Tumor (DNET) is a benign, WHO grade I glioneuronal tumor typically presenting in children and young adults with long-standing, pharmacoresistant epilepsy. The temporal lobe is the most common location.
Epidemiology
Age: Childhood to young adulthood (most < 20 years)
Slight male predominance
~80% of cases involve the temporal lobe
Clinical Presentation
Chronic, intractable focal epilepsy
Often normal neurological exam
Rarely causes increased intracranial pressure or neurological deficits