In order to enable more efficient research synthesis and to align research with patient needs, global initiatives have been formed that aim to develop standards for researchers. These processes use a multi-stakeholder consensus process to solicit knowledge, experience, and judgement from stakeholders with a broad range of direct interest on a particular issue and derive shared and relevant agreement. Stakeholders are defined as “individuals, organizations, or communities that have a direct interest in the process and outcomes of a project, research or policy endeavor.”