Preoperative radiological analysis with CT & MRI is inevitable in planning endonasal transsphenoid surgery to avoid complications because of the high variability concerned with sphenoid anatomy. Anatomical variations of sphenoid sinus esp. degree of pneumatization, sellar configuration, septation pattern, inter carotid distance were evaluated. Results were significant and in concordance with other similar studies. Most frequently encountered pneumatization was sellar type and least was conchal type Sphenoid sinus pneumatization is directly linked to safe access to sella. Presence of septae within sinus need to be identified preoperatively to avoid damage and confusion intraoperatively ¹⁾