Intermediate-acting, aminosteroid, a non-depolarizing muscle relaxant. The only nondepolarizing neuromuscular blocking agent approved for rapid sequence intubation. Duration of action and onset are dose-dependent.
In large doses, it has a speed of onset that approaches succinylcholine. However, in these doses, paralysis usually lasts ≈ 1–2 hrs. Expensive. ℞ Adult: initial dose 0.6–1 mg/kg. May be used as an infusion of 10–12 mcg/kg/min.