Renin

Renovascular disease is a well-described cause of hypertension, which is caused by the increase in renin secretion with subsequent increase in angiotensin and aldosterone but is found to be a primary cause in a minority of cases 1).

see Renin angiotensin system.

1)
Black HR, Glickman MG, Schiff M Jr, Pingoud EG. Renovascular hypertension: pathophysiology, diagnosis, and treatment. Yale J Biol Med. 1978 Nov-Dec;51(6):635-54. Review. PubMed PMID: 377821; PubMed Central PMCID: PMC2595593.