Resveratrol (Res), as a naturally occurring polyphenol mainly found in grapes and red wine, gives neuroprotection in a variety of experimental models for neurodegenerative diseases in vitro and in vivo 1).

1)
Zhang LN, Hao L, Wang HY, Su HN, Sun YJ, Yang XY, Che B, Xue J, Gao ZB. Neuroprotective effect of resveratrol against glutamate-induced excitotoxicity. Adv Clin Exp Med. 2015 Jan-Feb;24(1):161-5. doi: 10.17219/acem/38144. Review. PubMed PMID: 25923101.