Primary spinal dural diffuse large B-cell lymphoma is a rare type of non-Hodgkin's lymphoma that originates from the lymphatic tissue of the spinal dura mater, which is the outermost layer of the membrane that covers the spinal cord. This type of lymphoma is considered primary when it originates in the spinal dura mater and has not spread from other parts of the body.
Symptoms of primary spinal dural diffuse large B-cell lymphoma may include back pain, weakness, numbness or tingling in the limbs, difficulty walking, and incontinence. The diagnosis is usually made through imaging tests such as MRI and biopsy of the affected area.
Treatment for primary spinal dural diffuse large B-cell lymphoma typically involves a combination of chemotherapy and radiation therapy. In some cases, surgery may also be necessary to remove the affected tissue. The prognosis for this type of lymphoma varies depending on the stage and extent of the disease, but early diagnosis and treatment can significantly improve the chances of successful treatment and long-term survival.