Mesial temporal sclerosis (MTS) is a term used to describe scarring in the deep part of the temporal lobe.
Mesial temporal sclerosis (MTS) is the most common cause of intractable temporal lobe epilepsy.
The hippocampal formation is not uniformly affected, with the dentate gyrus, and the CA1, CA4 and to a lesser degree CA3 sections of the hippocampus being primarily involved. Histologically there is neuronal cell loss, gliosis and sclerosis.
Mesial temporal sclerosis (MTS) is the most common cause of intractable temporal lobe epilepsy.