Lumbar puncture complications

Lumbar puncture is a safe and commonly performed procedure, with an overall complication rate of 0.1% to 0.5%.

Post lumbar puncture spinal hematoma

Post lumbar puncture spinal hematoma


Post lumbar puncture headache

Bloody tap.

Dry tap.

Infection.

Dysesthesia.

Post–dural puncture cerebral herniation.


Under some circumstances, lumbar puncture cannot be performed safely (e.g. a severe bleeding tendency). It is regarded as a safe procedure, but post-dural-puncture headache is common.


Lapadula et al. report a case of a young man with epilepsy who, after a lumbar puncture performed for research purposes, presented with an intracerebral hematoma and neurological deficits. To the best of our knowledge, post-tap intraparenchymal hematoma is extremely rare and only 1 case has been reported previously. In consideration, all patients undergoing a lumbar puncture should be informed about this possible rare complication, even in the absence of documented hemorrhagic risk factors 1).


The Department of Neurosurgery, Hospital Network Antwerp, Belgium published a case of severe bilateral subdural hematomas as a complication of diagnostic lumbar puncture for possible Alzheimer's disease 2).

1)
Lapadula G, Caporlingua F, Caporlingua A, CurrĂ  A, Fattapposta F, Missori P. Delayed Intraparenchymal Hematoma Following Diagnostic Lumbar Puncture. Neurologist. 2015 Oct;20(4):70-3. doi: 10.1097/NRL.0000000000000055. PubMed PMID: 26468872.
2)
Verslegers L, Schotsmans K, Montagna M, Feyen B, De Jong L, Crols R, Engelborghs S. Severe bilateral subdural hematomas as a complication of diagnostic lumbar puncture for possible Alzheimer's disease. Clin Neurol Neurosurg. 2016 Dec 8;152:95-96. doi: 10.1016/j.clineuro.2016.12.003. [Epub ahead of print] PubMed PMID: 27978461.