Pathology There are four mechanisms by which intracranial dural metastases are thought to occur 1):
Direct extension from skull metastases
Retrograde seeding through the vertebral venous plexus
Haematogenous seeding
Lymphatic seeding
The primary malignancies that frequently cause dural metastases include (in descending order of frequency) 2) 3).
breast cancer
prostate cancer
lung cancer
head and neck cancers
haematological cancers
neuroblastoma
gastric adenocarcinoma 4).