Although certain intrinsic and extrinsic factors have consistently been found to be associated with a higher risk of rupture in various studies, there is still a lack of a complete understanding of the natural history of intracranial aneurysms. In addition, in further analysis of the known risk factors, some discrepancies start to emerge. For example, although aneurysm size is a well-documented risk factor, the optimal cutoff size is yet to be defined. Intracranial aneurysm location can also affect rupture risk independently of size. In addition, with the increasing number of population-based studies, certain reports of interracial differences have emerged, further adding to the complexity of the matter 1) 2).
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