IDH-mutant glioma outcome

The better outcome of IDH-mutant glioma is orchestrated exquisitely through epigenetic reprogramming that directs the bidirectional expression of neural stem-cell marker genes 1).

1)
Tiburcio PDB, Locke MC, Bhaskara S, Chandrasekharan MB, Huang LE. The neural stem-cell marker CD24 is specifically upregulated in IDH-mutant glioma [published online ahead of print, 2020 Jul 1]. Transl Oncol. 2020;13(10):100819. doi:10.1016/j.tranon.2020.100819