Hypothesis-generating refers to:
A type of study or analysis intended to explore possible associations, patterns, or effects that may inform future research, rather than to confirm or prove a predefined hypothesis.
🔍 Key Features:
Based on observational data, often retrospective
Lacks randomization, control groups, or strict blinding
May involve multiple outcomes or exploratory subgroup analyses
Not powered to provide definitive answers
Used to identify trends or suggest relationships worth studying further
⚠️ Important Clarification:
Hypothesis-generating ≠ Hypothesis-confirming
Hypothesis-generating studies raise questions
Hypothesis-confirming studies (e.g. RCTs) aim to answer them
🧠 Use in Critique:
Calling a study “hypothesis-generating” is a diplomatic way to point out that:
Its findings are not strong enough to change clinical practice
It may be overreaching in its conclusions