High-grade astrocytomas are fast-growing and often spread within the brain and spinal cord. There are several types of high-grade astrocytomas. High-grade astrocytomas can be either:
Grade III tumors–anaplastic astrocytoma or anaplastic pleomorphic xanthoastrocytoma.
Grade IV tumors–glioblastoma or diffuse midline glioma.
Childhood astrocytomas usually do not spread to other parts of the body.