Frontoethmoidal encephalocele are common in Southeast Asian countries, with an incidence of 1 in 5000 live births. These lesions affect children from the low socioeconomic class, but its etiology remains poorly understood 1).
Neural tube defects like spina bifida can lead to frontoethmoidal meningoencephaloceles. This suggests a role of folate deficiency, although there is not much documentation on the relationship between maternal folate levels and its incidence 2).