D-dimer (a specific fibrin degradation product): high levels are associated with Deep-vein thrombosis and PE 1).
D-dimer: a fibrin degradation product, showed a sensitivity of 97.1%, specificity of 91.2%, a negative predictive value of 99.6%, and a positive predictive value of 55.7% 2) for Cerebral venous sinus thrombosis diagnosis
A normal D-dimer level by a sensitive radioimmunoassay or ELISA may help identify patients with a low probability of cerebral venous thrombosis (Level II). However, if suspicion is high, further evaluation is indicated.