Table of Contents

Dexamethasone

Two commonly used corticosteroids are prednisone and prednisolone. Both are usually given as oral tablets. Prednisone is converted into prednisolone in the liver so that the effect of the two drugs is usually the same. Another corticosteroid, called dexamethasone, is more potent and is used in smaller doses.

Dexamethasone has comparatively low mineralocorticoid properties and high glucocorticoid potency 1).

In the early 1960s, Galichich and colleagues published their experience with dexamethasone in brain tumor patients 2).

Indications

see Dexamethasone Indications

Side effects

see Steroid side effects

1)
Dietrich J, Rao K, Pastorino S, et al. Corticosteroids in brain cancer patients: benefits and pitfalls. Expert Rev Clin Pharmacol. 2011;4(2):233–242.
2)
Galicich JH, French LA, Melby JC. Use of dexamethasone in treatment of cerebral edema associated with brain tumors. J Lancet. 1961;81:46–53.