Dabigatran reversal

• Thrombosis and Coagulopathy
• Diagnostics and management of direct oral anticoagulants-induced bleeding
• Anticoagulation strategies for stroke prevention in atrial fibrillation: a comprehensive review of current literature
• DOAC-Stop reverses the anticoagulant effect of asundexian and milvexian
• Sonorheometry parameters during dabigatran reversal with idarucizumab for major bleeding
• 2025 Guidelines for direct oral anticoagulants: a practical guidance on the prescription, laboratory testing, peri-operative and bleeding management
• Intravenous Dabigatran Provides Effective, Reversible Anticoagulation for Cardiopulmonary Bypass in a Sheep Model
• Reversal of anticoagulation in patients with intracerebral haemorrhage related to oral anticoagulants: State of the evidence

Idarucizumab is indicated for the reversal of life-threatening or uncontrolled bleeding or when emergency surgery or urgent procedures are required.

Dabigatran Reversal in Mild Traumatic Brain Injury

Despite these limitations and the fact that prothrombin complex concentrates and aPCCs are not yet licensed for dabigatran reversal, their use appears to be warranted in patients with life-threatening haemorrhage if idarucizumab is not available.