Choline (Cho): Marker of cell membrane turnover and proliferation, often elevated in tumors.
N-Acetylaspartate (NAA): Marker of neuronal integrity, typically reduced in areas of damage or tumor infiltration.
Interpretation:
Higher Cho/NAA: Indicates increased tumor activity, malignancy, or infiltrative processes.
Used to differentiate tumors from non-tumor conditions and to assess glioblastoma recurrence.
see Choline to N-Acetylaspartate Ratio in Glioblastoma Recurrence Diagnosis.