An abnormal protein level in the Cerebrospinal fluid suggests a problem in the central nervous system. Increased protein levels may be a sign of a tumor, bleeding, nerve inflammation, or injury. A blockage in the flow of spinal fluid can cause the rapid buildup of protein in the lower spinal area.
The normal protein range varies from lab to lab, but is typically about 15 to 60 milligrams per deciliter (mg/dL) or 0.15 to 0.6 milligrams per milliliter (mg/mL).
Normal value ranges may vary slightly among different laboratories.
Some laboratories use different measurements or may test different specimens.
Upon cerebrospinal fluid analysis, Mayol et al. found increased levels of cerebrospinal fluid proteins and other abnormal values in myelomeningocele population; however, none of the cultures grew any pathogens. This finding is an important tool in the evaluation of the possible etiologies of and therapeutic approaches for future shunt problems in this group of patients 1).