The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). It is a G protein-coupled receptor (GPCR), coupled to the Gi protein, that mediates inhibitory neurotransmission. The serotonin 1A receptor is encoded by the HTR1A gene.
5-HT1A agonists and dyskinesia in Parkinson's disease: a pharmacological perspective 1).