1998

1997-1999

First therapeutic report of temozolomide to treat human gliomas 1).

Intraosseous nerves within the vertebral body were described in 1998 by Antonacci et al 2).

In 1998, a group led by Dr. Jerry Oakes 3) identified five patients with syringomyelia and no evidence of tonsillar herniation (i.e. no Chiari I malformation).

Medtronic aquired Sofamor Danek in 1998.

Vicari in 1994 4) and Drs. Barone and Jimenez in 1998 5) introduced endoscopic-assisted craniosynostosis surgery followed by application of a molding helmet.

1)
Friedman HS, McLendon RE, Kerby T, et al. DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. J Clin Oncol 1998;16: 3851–7
2)
Antonacci MD, Mody DR, Heggeness MH. Innervation of the human vertebral body: a histologic study. J Spinal Disord. 1998 Dec;11(6):526-31. PubMed PMID: 9884299.
3)
Iskandar BI, Hedlund GL, Grabb PA, Oakes WJ. The resolution of syringomyelia without hindbrain herniation after posterior fossa decompression. J Neurosurg 1998;89: 212–216.
4)
Vicari F Endoscopic correction of sagittal craniosynostosis Paper presented at: Meeting of the American Society of Plastic Surgeons; September 25–28, 1994; San Diego, CA
5)
Jimenez DF, Barone CM. Endoscopic craniectomy for early surgical correction of sagittal craniosynostosis. J Neurosurg. 1998 Jan;88(1):77-81. PubMed PMID: 9420076.