1926

1925-1927

Charles Foix and Théophile Alajouanine first described the Foix-Alajouanine Syndrome in 2 young men (aged 29 y and 27 y), in 1926 1).

The first case was reported in 1837 by Magnus. The syndrome was described by Foix Chavany et Marie in 1926 2) , and called SFMC by Weller (1993). His literature review of 62 SFMC allowed the differentiation of five clinical types: the classical and most common form associated with cerebrovascular disease, a subacute form caused by central nervous system infections, a developmental form, a reversible form in children with epilepsy and a rare type associated with neurodegenerative disorders 3).

Brainstem tumors were first described by Kummel in 1881 4) and Monakow 5). The first nosological classification was reported in 1926 by Bailey and Cushing who emphasized, for the first time, that brainstem gliomas could develop from certain embryological cells 6).

1)
Foix C, Alajouanine T. La myélite nécrotique subaigue. Rev Neurol (Paris) 1926;2:1–42.
2)
Foix C, Chavany JA, Marie J (1926) Diplégie facio-linguomasticatrice d’origine souscorticale sans paralysie des membres (contribution à l’étude de la localisation des centres de la face du membre supérieur). Rev Neurol 33:214–219
3)
Laurent-Vannier A, Fadda G, Laigle P, Dusser A, Leroy-Malherbe V. [Foix-Chavany-Marie syndrome in a child caused by a head trauma]. Rev Neurol (Paris). 1999 May;155(5):387-90. Review. French. PubMed PMID: 10427603.
4)
Kummel B. Beitrag Zur Kasuistik Der Gliom Des Pons Und Der Medulla Oblongata. Klin Medizin. (1881).
5)
Monakow C. Histoire naturelle des tumeurs cérébrales, en particulier du gliome. Encéphale. (1926):117–89.
6)
Bailey P, Cushing H. A classification of tumors of the glioma group on a hystogenesis basis. Philadelphia: Lippincot; (1926).