The first bilateral intracranial acute epidural hematoma case was described by Roy in 1884 1).
The Frankfurt plane or Frankfort plane (both spellings are widely used, and the term is entered as Frankfort horizontal plane in several medical dictionaries, although Frankfurt is the modern standard spelling of the city it is named for) was established at the World Congress on Anthropology in Frankfurt am Main, Germany in 1884, and decreed as the anatomical position of the human skull.
Macrophages were first discovered by Élie Metchnikoff, a Russian bacteriologist, in 1884.