1824

1823-1825

As early as 1783, Monro, Kellie in 1823, and other investigators advanced the notion that the volume of the brain is constant 1) 2)

1)
Monro A (1783). Observations on the structure and function of the nervous system. Edinburgh: Creech & Johnson.
2)
Kellie G (1824). “Appearances observed in the dissection of two individuals; death from cold and congestion of the brain”. Trans Med Chir Sci Edinb. 1: 84–169.