====== Venous outflow ====== [[Venous outflow]] has been examined as a potential descriptor of the [[etiology]] of various diseases such as [[migraine]]s, [[tinnitus]], [[multiple sclerosis]], and [[Alzheimer’s disease]] ((Zakaria MMA, Mikhael SY, Hussein AKA, El-Din RAS, El-Malak HWA, Hewedi IH, Nadim HS. Failure of the vascular hypothesis of multiple sclerosis in a rat model of chronic cerebrospinal venous insufciency. Folia Neuropathol. 2017;55(1):49–59.)) ((Henry-Feugeas MC. Assessing cerebrovascular contribution to late dementia of the Alzheimer’s type: the role of combined hemodynamic and structural MR analysis. J Neurol Sci. 2009;283(1–2):44–8.)) However, results were often discouraging, with the exception of [[idiopathic intracranial hypertension]], where a model of functional coupling between [[intracranial pressure]] (ICP) and [[sagittal sinus]] [[pressure]] (SSP) has been produced ((Bateman GA. Association between arterial infow and venous outfow in idiopathic and secondary intracranial hypertension. J Clin Neurosci. 2006;13(5):550–6.)).