=====Upper motor neuron===== Upper [[motor neuron]]s are motor neurons that originate either in the [[motor cortex]] or in the [[brainstem]] and carry motor information down to the [[lower motor neuron]]s. The main effector or motor neurons (efferent neurons) for voluntary movement lie within layer V of the primary motor cortex and are a type of giant pyramidal cell called Betz cells. The cell bodies of these neurons are the largest in the brain, approaching nearly 0.1mm in diameter. see [[Upper motor neuron syndrome]].